Antiandrogens: Identifying & Avoiding Endocrine Disruptors

By Ali Kuoppala | Last reviewed Mon 24 September 2018

Medical Review by Dr. Stefano Pizzo, MD

Antiandrogens are compounds either natural or synthetic, that have the ability to lower the levels of testosterone and DHT (the androgens) and/or prevent the natural androgen pathways and their functions by blocking the androgen receptors in tissue.

Limiting your exposure to antiandrogenic compounds plays a key part in natural hormone optimization, and in my opinion, it’s far more important than say; supplementation would be…

Sure, I get that it isn’t nearly as cool to tell people to avoid this chemical and that drug, when I could be putting this energy into promoting some ancient herb that would increase your testosterone levels by 10-50% with only three gel-caps, according to the old memoirs of an Indian Shaman…

…But really, this stuff is more important.

There are far more compounds we are exposed to on a daily basis that can lower our testosterone levels, than there are those of that could increase testosterone.

Antiandrogenic Prescription Drugs & Medication

antiandrogenic medication listI’m not a doctor, nor do I intend to play one online.

Keep that in mind when you’re reading this information about antiandrogenic drugs. This is certainly not medical information, and you should always discuss with your doctor before stopping or switching medication to more suit your needs and goals.

With that being said, there are many commonly used prescription drugs that have the ability to lower testosterone levels and block androgen receptors. Sometimes these are well-known side effects, and sometimes people have absolutely no clue how badly their medication can suppress their hormonal health.

Here is a short list of some of the more common antiandrogenic drugs;

Like said, if you are being prescribed some of the drugs above, don’t just blindly stop taking them. Discuss with your doctor if there are better alternatives for you and respect their views. So many people self-diagnose on the internet (poorly) and doctors are used to battling with these people on a daily basis. Don’t be like the ones that read some woo-woo and immediately think all doctors are evil. Work with yours and respect each other’s opinions instead.

Antiandrogenic Supplements and Nutraceuticals

antiandrogenic supplements that lower testosterone levelsTestosterone boosting supplements are a big, big, massively humongous multimillion-dollar business.

Most of the supplements from this branch of over the counter nutraceuticals, however, don’t do a thing for testosterone production. Some certainly do work to slightly increase testosterone levels, but did you know, that quite many of them actually are antiandrogens?

Yes, that’s right, an alarming amount of natural supplements can lower testosterone levels, and to top it all of, many of these are actually sold as testosterone boosters.

It’s absolutely insane if you ask me, but as long as people empty their wallets to the companies manufacturing bullshit T-boosters in a shiny bottle, nothing is going to change.

Below are antiandrogenic nutraceutical supplements to avoid;

The list above isn’t definitive, as there are plenty of other natural compounds that have antiandrogenic activity in terms of blocking testosterone and DHT synthesis or acting as androgen receptor antagonists. Which is why when taking supplements, it’s good to do some research on the compounds hormonal effects before buying into other health claims.

Antiandrogenic Chemicals and Compounds

chemicals and other antiandrogens

Last but not least, there are several antiandrogenic compounds in our everyday items and groceries.

Mostly these are man-made chemicals and/or already banned compounds which are still stuck in the soil and are therefore transferred to our foods and produce.

Not only in foods but chemical antiandrogens such as the popular “xenoestrogens” can also be found in many types of plastics, receipts, toilet paper, air fresheners, you name it…

Here’s a list of the most common ones;

With tens of millions of different man-made chemicals in production, it’s impossible to identify all of the antiandrogens. While many of the chemicals are likely very safe, there will still always be the ones that are antiandrogens and thus lower testosterone and DHT levels and activity. It would be easy to blame the manufacturers, but the fact is that these chemicals are also incredibly useful and working to stop their production would be a fight against the impossible. You as a consumer have the ability to largely choose what you consume and what you’re exposed to…

…Small things like switching to metal drinking bottle (affiliate link), getting rid of air fresheners, eating less processed foods, and switching to natural personal care items will greatly reduce your exposure to antiandrogenic compounds with barely any work needed on your part.

Ali Kuoppala

Ali Kuoppala is the founder of Anabolic Men. He has authored and co-authored multiple men's health books and focuses on uncovering the methods of optimizing hormonal health. To date, his articles on various websites have been read more than 15-million times. To read more about Ali, visit his Medium article.